microbial Profiling Using Metagenomic Assembly

A software package designed to allow researchers to profile microbial communities using a de novo assembly approach to form Operational Taxonomic Units (OTUs). While originally designed to support the analysis of cpn60 based amplicons, mPUMA can be used to analyze data from any suitable DNA barcode.


Links MG, Chaban B, Hemmingsen SM, Muirhead K, Hill JE: mPUMA: a computational approach to microbiota analysis by de novo assembly of OTUs based on protein-coding barcode sequences. Microbiome 2013, 1:23.

Help / Contact

If you have questions about installation of mPUMA or additional approaches for handling fastq data (e.g. paired-end) please contact the project admin as we may be able to help.